Clinical Director

Pfizer Clinical Director - Collegeville, Pennsylvania

The Clinical Lead (CL), Internal Medicine RU (IMRU) will be the thought leader driving clinical research for the expanding area of metabolic diseases at Pfizer. S/he will be responsible for creating the overarching strategy for early clinical development programs with a focus on innovative design, medical and scientific excellence, and the highest ethical standards. He or she will lead clinical development strategy and program execution of research projects with a particular focus on obesity and associated conditions (e.g., cardiovascular disease, renal impairment, diabetes, etc.), and lead translation of pre-clinical observations into clinical experiments and studies designed to demonstrate proof of pharmacology, proof of mechanism and proof of concept for new candidate medicines.

ROLE RESPONSIBILITIES

1. Uses deep medical and scientific knowledge and expertise to contribute to selection of targets for progression from chemical/biologic synthesis to testing in human.
2. Leads the creation of the clinical development plan from pre-clinical stages through to proof of concept.
3. Guides clinical team members to ensure excellence in development and translation of clinical research plans into efficiently delivered studies.
4. Oversees the design and execution of clinical research studies including development of outline/core elements prepared by Clinicians or other clinical team members.
5. Accountable for development of clinical documents (e.g., protocol, clinical report, clinical components of regulatory submissions).
6. Serves as a Medically Qualified Individual (MQI) at Pfizer, reviewing clinical trial data for safety signal identification and tracking.
7. Provides input to the operational strategy and feasibility of clinical research studies.
8. Establishes relationships with key clinical experts/sites and uses this information to advise the clinical team on site selection.
9. Flexible in supporting a dynamic research portfolio; may need to manage multiple programs in parallel.
10. Contributes to technical and protocol review committees across the portfolio.

QUALIFICATIONS

1. MD or MD/PhD (or equivalent degree(s)) with relevant postgraduate clinical training.
2. Approximately 8-10 years relevant experience.
3. Preference for established record in execution of clinical trials in the pharmaceutical industry environment.
4. Scientific excellence with deep knowledge of integrated metabolism biology and metabolic diseases.
5. Superior clinical ability with relevant disease area knowledge and experience.
6. Ability to design, initiate and conduct effective clinical studies.
7. Strong understanding of clinical regulatory requirements, and knowledge of GCP and ICH guidelines.
8. Experienced with ownership of budgets and sound financial risk management.
9. Ability to review and understand emerging data and proactively implement measures to ensure delivery of quality study results.
10. Skilled communicator and team leader.
11. Ability to navigate a complex matrixed environment.

PREFERRED QUALIFICATIONS

1. Board eligibility/certification in Internal Medicine, with subspecialty training in obesity medicine and/or endocrinology preferred.
2. Active medical license preferred.

The annual base salary for this position ranges from $213,500.00 to $355,800.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 25.0% of the base salary. We offer comprehensive benefits to help our colleagues lead healthy lives. Learn more at Pfizer Candidate Site - U.S. Benefits.

Relocation assistance may be available based on business needs and/or eligibility.

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Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants.