Senior Scientist II, Pathology

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

We are seeking a highly motivated individual to work within the Precision Medicine Pathology Group to develop and implement tissue-based assays to support drug development in oncology and other therapeutic areas. The Senior Scientist will drive the design, implementation and analysis of diagnostic and translational tissue-based biomarkers & participate in target discovery and validation projects.

This role will accomplish this by conducting histopathological evaluation as well as computer-based image analysis of IHC and other tissue-based assays, as well as by providing technical/scientific leadership in these areas.

The successful candidate will have the opportunity to work in a highly collaborative environment and will participate as a member of multidisciplinary, cross-functional discovery, translational, and development project teams.

Major Responsibilities

• Design, validate, and implement histochemical, IHC, and IF staining using Leica Autostainer XL, Ventana Discovery ULTRA, and Leica BOND RX platform.
• Perform routine histological procedures including tissue accessioning, gross-dissection, tissue processing, embedding, sectioning, staining and image capture of frozen and FFPE tissues.
• Perform image capture (whole slide scanning), data entry and organization.
• Perform image analysis using HALO and Visiopharm technologies.
• Generate data and present findings to relevant project teams in departmental and cross-functional meetings.
• Lead and maintain external vendor collaborations and relationships.
• Train staff in image analysis, quantification, and spatial biology techniques.
• Evaluate and bring in new and innovative image analysis and spatial biology tools and techniques.

Qualifications

• Bachelor’s Degree in Science related field with 15+ years of related work; Master’s Degree Science with 10+ years of related work; PhD in Science or related field with 4+ years of related work experience. (*Cancer Biology, Physiology, Cell Biology or a related field)
• Strong familiarity with the principles of tissue microscopic anatomy/histology.
• Experience working in collaboration with trained pathologists.
• Hands-on experience with development of immunohistochemistry (IHC) and other tissue-based assays including immunofluorescence (IF) multiplexing and in situ hybridization (ISH) preferred.
• Expertise in quantitative image analysis software and its application to IHC and other tissue-based staining modalities.
• Excellent verbal communication skills are required including the demonstrated ability to effectively and clearly summarize results for presentation and report generation.

Strong motivation, attention to detail, ability to think independently and fully integrate into a high achieving team environment.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit