Director Pathologist Global Pathology – CVRM Therapy Area
Are you a medical/veterinary pathologist with expertise in toxicologic or disease area pathology and want to help us deliver safe and effective new medicines to patients? This is an exciting opportunity to join a team of highly skilled pathologists to continue to push the boundaries of science!
AstraZeneca is looking for a dynamic and experienced Medical/Veterinary Pathologist to support our work in the Cardiovascular, Renal and Metabolism (CVRM) disease area. This role is broad in scope and offers significant potential for professional development. You will be based in Gaithersburg, US .
Pathology works closely with the CVRM disease area scientists and the Safety Sciences organization, providing integrated support covering all aspects of efficacy and safety pathology to drive the design, selection, and successful development of novel treatments for patients with cardiovascular, renal and metabolic diseases. The Global Pathology department works across Sweden, UK and US covering all aspects of pathology for all AstraZeneca disease areas. Pathology sits within Clinical Pharmacology and Safety Sciences (CPSS), which contains all non-clinical safety functions that support the entire AstraZeneca portfolio.
What you’ll do
As a Pathologist, you will work closely with discovery safety specialists and toxicologists as well as disease area scientists, providing expert anatomic pathology support to multiple drug projects across all development stages. You’ll contribute to the design and assessment of investigative safety and efficacy studies, ensuring timely delivery of high-quality pathology data. The AstraZeneca portfolio is modality agnostic, and you will get exposure to projects exploring small molecules, biologics, oligonucleotides, cell therapies, and more. While most of your work will be in the CVRM space, you will also have the opportunity to support our global portfolio in the Respiratory & Immunology, Vaccines & Immune Therapies, and Oncology therapy areas.
You will work closely with our expert team of Imaging & AI scientists, with access to state-of-the-art tissue imaging platforms, exploring multi-omics and AI to drive translational quantitative pathology. We rely on you to build effective cross-functional networks across Pathology, CPSS, and Early CVRM and with a curious mind seek opportunities for collaboration on safety and efficacy (e.g., animal model development, multimodal and in vivo imaging, mechanistic toxicology, and disease pathophysiology). You are expected to provide a comprehensive view of translational safety and efficacy pathology and pathophysiology from animal to patient.
Requirements
MD or DVM Pathology degree
Postgraduate pathology qualification (e.g., FRCPath, ESP, DACVP, DECVP, or DJSTP).
A minimum of 5 years’ experience in either toxicologic pathology or in a diagnostic area relevant to cardiovascular, renal or metabolic disease that includes cross-species research.
Genuine interest in providing broad disease area, discovery, and toxicologic pathology support and acting as a pathology representative on multiple drug development projects.
Strong familiarity with complementary data sets (e.g., clinical pathology, IHC, ISH, MSI); ability to integrate pathology findings with a range of traditional and novel endpoints and provide contextualized interpretation for project teams.
Highly effective written and communication skills with the ability to clearly convey complex pathology data to a wide range of stakeholders.
Willingness to embrace and champion the use of digital technology for all aspects of pathology and delivery of quantitative pathology data.
Desirable in the role
PhD in a subject relevant to toxicologic pathology or cardiovascular, renal or metabolic disease.
Strong scientific track record with publications in high-quality journals post-PhD.
Broad cross-species toxicologic pathology expertise with experience of histopathological evaluation and/or peer review.
More information
If you are a medical/veterinary pathologist seeking a new challenge, please get in touch with Magnus Söderberg at for an informal discussion about this exciting opportunity!
Why AstraZeneca?
At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth, and development. We’re on an exciting journey to pioneer the future of healthcare.
When we put unexpected teams in the same room, we ignite ambitious thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace, and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca's Biopharmaceuticals R&D division, we are driven by our desire to understand and reveal new insights. We follow the science to explore and innovate, working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. We are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. It's our combination of curiosity and courage that drives us, inspired by the possibility of doing things that have never been done before. We celebrate our successes and failures along the way. We are committed to making a difference and improving patient access to healthcare globally. Our values guide everything we do at AstraZeneca. They power our belief in What Science Can Do.
Are you ready to work with curious minds in an inclusive culture? Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment. Here all doors are open, and every voice is heard. From working side-by-side with academia to innovating with biotech, we are forever expanding our horizons. By sharing and increasing our knowledge we are empowered to be the best we can be and accelerate progress.
Join us today and be part of a team that makes a bigger impact on patients' lives!
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