Sr. Principal RA/Associate Scientist/Scientist I, Protein Chemistry

Company:  Omeros Corporation
Location: Seattle
Closing Date: 31/10/2024
Salary: £200 - £250 Per Annum
Hours: Full Time
Type: Permanent
Job Requirements / Description

Sr. Principal RA/Associate Scientist/Scientist I, Protein Chemistry


Position Summary:

Protein Chemistry provides expertise in protein design, production, and analytics to support the discovery and early development of bio-therapeutics across disease states. This position will design and execute experiments towards the production of high-quality protein reagents. Furthermore, the position will have responsibilities in developing and implementing protein production technologies.


Essential Duties & Responsibilities:

  • Develops and implements core protein production technologies towards the generation and screening of high-quality protein reagents
  • Maintains data integrity with detailed and up-to-date electronic lab notebooks and data documents
  • Interprets and presents findings at the group and department level
  • Collaboratively guides efforts toward selection of candidate therapeutic modalities in matrix environment

Education, Experience, Skills, and Knowledge Required:

  • With a protein sciences focus, minimum education requirements include either a BS degree with a minimum of 3+ years (8+ years) of relevant industry experience; a MS degree with 1+ years (4+ years) of relevant industry experience; a PhD with 0-2 years of relevant experience; (level will be based on relevant years of experience, skills, and knowledge the candidate has)
  • Experience applying technical skills towards recombinant protein expression, such as vector construction, use of expression systems (E. coli and HEK) and protein purification (AKTA, Chromatography)
  • Experience with determination of protein quality attributes, including purity, size, aggregation state, and endotoxin
  • Experience with biophysical and protein analytical techniques such as: UPLC (Reversed Phase, aSEC, aCEX, aHIC), Mass-spec, SPR, or Octet

Behavioral Competencies Required:

  • Builds collaborative relationships at the group and interdepartmental levels
  • Provides interpretation of production and functional relationship results to help guide selection of therapeutic modalities

Physical Demands Required:

  • Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 20 lbs.
  • May encounter prolonged periods of sitting or standing
  • This position requires working around hazardous materials

Compensation and Benefits:

Omeros is proud to offer a competitive total compensation package designed to support the lives of our employees and their families. The wage scale for the Sr. Principal RA/Associate Scientist/Scientist I, Protein Chemistry role is $95,000 - $128,000. Salaries will be determined based on knowledge, skills, education, and experience relevant to the role. Employees are offered medical, dental, vision, life insurance, and a 401(k) plan with a company match. Employees accrue three weeks of vacation and 80 hours of sick time on an annual basis and receive twelve paid holidays throughout the calendar year. This position is eligible for bonus and stock options.

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