SENIOR RESEARCH SCIENTIST, PROTEOMICS

Senior Research Scientist, Proteomics

Req #: 238960
Department: GENOME SCIENCES
Job Location: Seattle Campus
Posting Date: 09/16/2024
Closing Info: Open Until Filled
Salary: $9,583 - $11,083 per month
Shift: First Shift
Benefits: As a UW employee, you will enjoy generous benefits and work/life programs.

As a UW employee, you have a unique opportunity to change lives on our campuses, in our state and around the world. UW employees offer their boundless energy, creative problem-solving skills and dedication to build stronger minds and a healthier world. The Department of Genome Sciences (GS) is part of the University of Washington School of Medicine and is comprised of 31 labs addressing leading edge questions in biology and medicine by developing and applying genetic, genomic and computational approaches.

The Senior Research Scientist will lead, present on, apply for funding for, and manage training for multiple projects across multiple labs, including national and international collaborations, using high-throughput mass spectrometry, computational approaches, and proteomics sample preparation.

1. Computational and technical leadership within the UW Proteomics Resource (50%)
   
   • Collaborate on research, preparation, analysis and software development with UWPR users, the University’s proteomics researchers, and the national and global proteomics communities.
   • Develop and carry out targeted and discovery-based quantitative proteomics methods.
   • Provide technical expertise for the computational resource for the UW Proteomics Resource (UWPR).
   • Lead the acquisition, maintenance and operation of high performance mass spectrometers.
   • Prepare protein and biological samples for analysis by mass spectrometry.
   • Develop and run quality control steps to ensure mass spectrometers are tuned and analyses can deliver accurate results.
   • Lead the training and supervision of UW researchers in operation of mass spectrometry instrumentation.
   • Advise users of the UWPR on assay development and implementation.
   • Maintain accurate records of all aspects of lab experiments.
2. Computational and research leadership for proteomics and chemoproteomics method development (50%)
   
   • Lead large national and international projects and collaborations.
   • Independently develop innovative proteomic and computational methods.
   • Lead internal teams for the development and implementation assays.
   • Lead the maintenance of lab instrumentation.
   • Lead the analysis of data generated by sample multiplexed and targeted proteomics methods.
   • Manage data analysis pipelines using lab software.
   • Develop computational tools for proteomics analysis.
   • Train and collaborate with internal and external users on computational approaches.
   • Present research and research tools at national and international events.
   • Participate in research-related discussion during weekly lab meetings.
   • Lead the preparation and writing of grant applications.
   • Manage budgets and subbudgets for projects and collaborations.
   • Prepare, write, and submit manuscripts.

1. PhD in Biochemistry, Chemistry, Biology, or related field.
2. At least 6 years of experience in proteomics including protein sample processing, data analysis, mass spectrometry, and proteomics-related coding.

1. At least 10 years of experience working with Thermo Fisher instrumentation.
2. Experience teaching computational and proteomics courses.
3. Experience with routine protein sample handling and purification techniques.
4. Experience analyzing multiple different types of proteomics samples and assays.
5. Experience maintaining mass spectrometers.
6. Experience writing and coding with R, Python, C#, and C++.
7. Experience in Linux, and interaction with institutional IT teams.
8. Experience leading computational teams for software development.
9. Experience managing code and repositories using git and GitHub.
10. Experience presenting at national and international meetings.
11. Experience leading grant applications.
12. Must have demonstrated experience in the form of publications.
13. A deep understanding of proteomics methods and technologies.
14. Must be able to successfully work on multiple projects simultaneously.
15. Must be self-motivated and able to take initiative.
16. Must be able to perform repetitive but delicate work with care.
17. Excellent communication skills and meticulous record-keeping skills.
18. Strong organizational abilities.

1. Occasionally lifts and/or carries objects weighing up to 30 pounds.
2. Occasionally stoops and bends.
3. Occasionally reaches and grasps with arms and hands.

Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.

The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.

To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or

Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct.