Senior Scientist, Translational Pharmachology

Company:  Cue Biopharma
Location: Boston
Closing Date: 28/10/2024
Salary: £150 - £200 Per Annum
Hours: Full Time
Type: Permanent
Job Requirements / Description

The Company

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, is developing a novel class of therapeutic biologics to selectively engage and modulate disease-specific T cells to transform the treatment of cancer and autoimmune and inflammatory diseases. Cue Biopharma is a high growth company and is listed on NASDAQ: CUE. The company is located in Boston, Massachusetts in the heart of the life sciences corridor.

Cue Biopharma is building a world-class team of highly motivated, dedicated scientists to help advance its research and development programs. The company culture is fast-paced and committed to scientific excellence, innovation and teamwork.

Candidate Profile

The successful candidate will have a strong scientific background and laboratory skills in immunology, regulatory T cell biology, and/or autoimmunity with experience developing novel therapeutic approaches using in vitro and in vivo models. Preferred experience includes knowledge of regulatory T cell biology and autoimmunity, CRO management, and designing focused preclinical in vivo studies that assess immunologic endpoints to support pipeline assets and programs.

Key Responsibilities

  • Design and execute effective and efficient studies to address critical program needs.
  • Oversee and manage external vendors to execute in vitro and in vivo studies that assess Treg function in models of autoimmunity.
  • Deliver sample analysis endpoints for preclinical studies aimed at building pharmacologic relationships between drug exposure, target engagement and activity of Cue Biopharma’s molecules.
  • Ensure appropriate study documentation, analyze and interpret data and clearly communicate results within the organization.
  • Author and review technical reports and summary documents for regulatory filings, scientific presentations and publications.
  • Work collaboratively with members of the translational pharmacology team in a matrixed fashion to achieve team goals and support organizational goals.

Requirements

  • Minimum Requirements: B.Sc. with 10-12+ years of industry research experience, and a track record of supporting advancement of novel therapeutic modalities or M.Sc. with 8-10 years of industry research experience.
  • Preferred Requirements: Ph.D. in Immunology or related field with 5-8 years industry research experience.
  • Direct experience with immune regulation and Treg cell biology, mouse models of inflammation and/or autoimmunity, as well as cell-based assays to assess human Treg function.
  • Experience with B cell biology and/or therapeutic targeting in the context of autoimmunity is a plus.
  • Scientifically rigorous with significant attention to detail.
  • Ability to work well with external CROs, consultants and collaborators.
  • Ability to work effectively both independently and collaboratively in a fast-paced, dynamic team-oriented environment.
  • Outstanding organizational skills with the ability to prioritize and simultaneously deliver against timelines for multiple projects.
  • Self-motivated, team- and goal-oriented scientist with excellent oral and written communication skills.

Equal Employment Opportunity Policy

Cue Biopharma champions equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected military or veteran status, marital or registered civil partnership status, pregnancy or parental status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Cue Biopharma will endeavor to ensure that any individual with disabilities who is qualified for the position in question is provided reasonable accommodation to participate in the job application process.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

Job Type: Full-time

Benefits:

  • 401(k)
  • Dental insurance
  • Flexible schedule
  • Flexible spending account
  • Health insurance
  • Life insurance
  • Paid time off
  • Parental leave
  • Vision insurance

Schedule:

  • Monday to Friday

Work Location: In person

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